The Cialis brand of tadalafil is used in men to treat erectile dysfunction (impotence) and symptoms of benign prostatic hypertrophy (enlarged prostate).
Adcirca and Alyq are used in men and women to treat pulmonary arterial hypertension (PAH) and to improve exercise capacity.
Do not take Cialis for erectile dysfunction if you are taking Adcirca or Alyq for pulmonary arterial hypertension.
Tadalafil may also be used for purposes not listed in this medication guide.
You should not take tadalafil if you are allergic to it, or:
if you take other medicines to treat pulmonary arterial hypertension, such as riociguat (Adempas).
Do not take tadalafil if you are also using a nitrate drug for chest pain or heart problems. This includes nitroglycerin, isosorbide dinitrate, and isosorbide mononitrate. Nitrates are also found in some recreational drugs such as amyl nitrate, butyl nitrate or nitrite ("poppers"). Taking tadalafil with a nitrate medicine can cause a sudden and serious decrease in blood pressure. Some tadalafil can remain in your bloodstream for 2 or more days after each dose you take (longer if you have liver or kidney disease). Avoid nitrate use during this time.
Tell your doctor if you have ever had:
- heart problems (chest pain, a heart rhythm disorder, heart failure);
- a heart attack or stroke;
- high or low blood pressure;
- liver disease;
- kidney disease (or if you are on dialysis);
- retinitis pigmentosa (an inherited condition of the eye);
- blindness in one or both eyes;
- hearing problems;
- blood circulation problems;a blood cell disorder such as sickle cell anemia, multiple myeloma, or leukemia;
- pulmonary veno-occlusive disease (PVOD);
- a physical deformity of the penis (such as Peyronie's disease), or an erection lasting longer than 4 hours;
- a stomach ulcer; or
- health problems that make sexual activity unsafe.
A small number of people taking tadalafil have had sudden vision loss. Most of these people already had eye problems, or had diabetes or other health conditions that can affect blood vessels in the eyes. It is not clear whether tadalafil causes vision loss. Do not start or stop taking tadalafil during pregnancy without your doctor's advice. Having pulmonary arterial hypertension (PAH) during pregnancy may cause heart failure, stroke, or other medical problems in both mother and baby. Tell your doctor right away if you become pregnant. It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk. Cialis is not for use in women. Tadalafil is not approved for use by anyone younger than 18 years old.
Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using tadalafil and call your doctor at once if you have:
- heart attack symptoms--chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating;
- vision changes or sudden vision loss;
- ringing in your ears or sudden hearing loss; or
- an erection is painful or lasts longer than 4 hours (prolonged erection can damage the penis).
Stop and get medical help at once if you have nausea, chest pain, or dizziness during sex. You could be having a life-threatening side effect.